Which of the following is the most common side effect of tissue plasminogen activator (tpa)?11/10/2022 ![]() ![]() □ (A) Autophagy by lysosomes □ (B) Clumping of nuclear chromatin □ (C) Defects in the cell membraneĦ A 38-year-old woman experienced severe abdominal pain with hypotension and shock that led to her death within 36 hours after the onset of the pain. The increase in this patient's serum enzyme levels most likely results from which of the following changes in the hepatocytes? Laboratory findings include a serum AST of 68 U/L, ALT of 75 U/L, and total bilirubin of 5.1 mg/dL. On physical examination, he has minimal right upper quadrant tenderness. Microscopically, which of the following materials can be found in abundance in the form of crystals that produce long, cleft-like spaces? □ (A) Glycogen □ (B) Lipofuscin □ (C) Hemosiderin □ (D) Immunoglobulin □ (E) Cholesterolġ A 17-year-old boy infected with hepatitis A experiences mild nausea for about 1 week and develops very mild scleral icterus. The curetted atheromatous plaque has a grossly yellow-tan, firm appearance. A right carotid endarterectomy is performed. On physical examination, she has an audible bruit on auscultation of the neck. If his hypertension remains untreated for years, which of the following cellular alterations would most likely be seen in his myocardium? □ (A) Atrophy □ (B) Hyperplasia □ (C) Metaplasia □ (D) Hemosiderosis □ (E) Hypertrophyĥ A 69-year-old woman has had transient ischemic attacks for the past 3 months. ![]() Kindle Edition.ģ On a routine visit to the physician, an otherwise healthy 51-year-old man has a blood pressure of 150/95 mm Hg. Robbins and Cotran Review of Pathology E-Book (p. Which of the following processes best explains this CT scan finding? □ (A) Apoptosis □ (B) Dysplasia □ (C) Fatty change □ (D) Hydropic change □ (E) Hyperplasia □ (F) Hypertrophy □ (G) Metaplasia Several weeks later, a CT scan of the abdomen shows that the liver has nearly regained its size before the injury. Peritoneal lavage shows a hemoperitoneum, and at laparotomy, a small portion of the left lobe of the liver is removed because of the injury. Kindle Edition.Ģ A 16-year-old boy sustained blunt trauma to the abdomen when the vehicle he was driving struck a bridge abutment at high speed. □ (B) Dystrophic calcification □ (C) Lipofuscin deposition □ (D) Hemosiderosis □ (E) Fatty change Which of the following pathologic processes best accounts for the appearance of the aortic valve seen in the figure? □ (A) Amyloidosis A serum chemistry panel ordered before death showed no abnormalities. At autopsy, the heart weighed 580 g and showed marked left ventricular hypertrophy and minimal coronary arterial atherosclerosis. ![]() doi:10.1001/jama.2014.4 A 72-year-old man died suddenly from congestive heart failure. Door-to-needle times for tissue plasminogen activator administration and clinical outcomes in acute ischemic stroke before and after a quality improvement initiative. Time to treatment with intravenous tissue plasminogen activator and outcome from acute ischemic stroke. A case-control study of the effectiveness of tissue plasminogen activator on 6 month patients-reported outcomes and health care utilization. Lang CE, Bland MD, Cheng N, Corbetta M, Lee JM. Safety of intravenous thrombolysis for acute ischemic stroke in specific conditions. 2018 Guidelines for the early management of patients with acute ischemic stroke: A guideline for healthcare professionals from the American Heart Association/American Stroke Association. Powers WJ, Rabinstein AA, Ackerson T, et al. ![]()
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